Mini CV
2013: PhD « Role of oestrogen et nouvelles approches thérapeutiques” University Toulouse III
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expertise
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Recherche/projet research/project
Identify new bioactive molecules modulating the “gut-brain-peripheral axis” to improve glucose metabolism disorders
Evaluate the therapeutic potential of modulating the "gut-to-brain" axis activity to treat metabolic disease including Type 2 diabetes.
Evaluate the therapeutic potential of modulating the "gut-to-brain" axis activity to treat metabolic disease including Type 2 diabetes.
Production scientifique scientific production
- Glucosensing in the gastrointestinal tract: Impact on glucose metabolism, Fournel A, Marlin A, Abot A, Pasquio C, Cirillo C, Cani PD, Knauf C., Am J Physiol Gastrointest Liver Physiol. 2016 Mar 3:ajpgi.00015.2016.
- The uterine and vascular actions of Estetrol delineate a distinctive profile of Estrogen Receptor α modulation, uncoupling nuclear and membrane activation. Abot A, Fontaine C, Solinhac R, Drougard A, Fabre A, Rajan S, Laine M, Buscato M, Milon A, Henrion D, Mestdagt M, Raymond-Letron I, Knauf C, Gourdy P, Flouriot G, Katzenellenbogen BS, Katzenellenbogen JA, Lenfant F, Greene GL, Foidart JM and Arnal JF, EMBO Mol Med. 2014 Sep 11;6(10):1328-46.
- Mutation of the palmitoylation site of estrogen receptor α in vivo reveals tissue-specific roles for membrane versus nuclear actions. Adlanmerini M, Solinhac R, Abot A, Fabre A, Raymond-Letron I, Guihot AL, Boudou F, Sautier L, Vessières E, Kim SH, Lière P, Fontaine C, Krust A, Chambon P, Katzenellenbogen JA, Gourdy P, Shaul PW, Henrion D, Arnal JF, Lenfant F, Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):E283-90.
- Association between adiponectin and cartilage degradation in human osteoarthritis. Francin PJ, Abot A, Guillaume C, Moulin D, Bianchi A, Gegout-Pottie P, Jouzeau JY, Mainard D, Presle N. Osteoarthritis Cartilage. 2014 Mar;22(3):519-26