Mini CVEDUCATION
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expertiseQuantitative PCR, western blot, histology , immunofluorescence, confocal microscopy
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RESEARCH/PROJECT
Iron metabolism regulation during inflammatory and infectious processes
SCIENTIFIC PRODUCTION
Further support for the association of GNPAT variant rs11558492 with severe iron overload in hemochromatosis. Besson-Fournier C, Martinez M, Vinel JP, Aguilar-Martinez P, Coppin H, Roth MP.Hepatology. 2016 Jun;63(6):2054-5. doi: 10.1002/hep.28259. Epub 2015 Oct 30. No abstract available.
Differing impact of the deletion of hemochromatosis-associated molecules HFE and transferrin receptor-2 on the iron phenotype of mice lacking bone morphogenetic protein 6 or hemojuvelin.Latour C, Besson-Fournier C, Meynard D, Silvestri L, Gourbeyre O, Aguilar-Martinez P, Schmidt PJ, Fleming MD, Roth MP, Coppin H.
Hepatology. 2016 Jan;63(1):126-37.
Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin.
Latour C, Kautz L, Besson-Fournier C, Island ML, Canonne-Hergaux F, Loréal O, Ganz T, Coppin H, Roth MP.
Hepatology. 2014 Feb;59(2):683-94.
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Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling.
Besson-Fournier C, Latour C, Kautz L, Bertrand J, Ganz T, Roth MP, Coppin H.
Blood. 2012 Jul 12;120(2):431-9
Iron overload induces BMP6 expression in the liver but not in the duodenum.
Kautz L, Besson-Fournier C, Meynard D, Latour C, Roth MP, Coppin H.
Haematologica. 2011 Feb;96(2):199-203.
BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.
Kautz L, Meynard D, Besson-Fournier C, Darnaud V, Al Saati T, Coppin H, Roth MP.
Blood. 2009 Sep 17;114(12):2515-20
Differing impact of the deletion of hemochromatosis-associated molecules HFE and transferrin receptor-2 on the iron phenotype of mice lacking bone morphogenetic protein 6 or hemojuvelin.Latour C, Besson-Fournier C, Meynard D, Silvestri L, Gourbeyre O, Aguilar-Martinez P, Schmidt PJ, Fleming MD, Roth MP, Coppin H.
Hepatology. 2016 Jan;63(1):126-37.
Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin.
Latour C, Kautz L, Besson-Fournier C, Island ML, Canonne-Hergaux F, Loréal O, Ganz T, Coppin H, Roth MP.
Hepatology. 2014 Feb;59(2):683-94.
.
Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling.
Besson-Fournier C, Latour C, Kautz L, Bertrand J, Ganz T, Roth MP, Coppin H.
Blood. 2012 Jul 12;120(2):431-9
Iron overload induces BMP6 expression in the liver but not in the duodenum.
Kautz L, Besson-Fournier C, Meynard D, Latour C, Roth MP, Coppin H.
Haematologica. 2011 Feb;96(2):199-203.
BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.
Kautz L, Meynard D, Besson-Fournier C, Darnaud V, Al Saati T, Coppin H, Roth MP.
Blood. 2009 Sep 17;114(12):2515-20