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  • HOME
  • About
    • DIRECTION
  • Research
    • teams >
      • TEAM 1 PATHOPHYSIOLOGY OF THE INTESTINAL EPITHELIUM
      • ​TEAM 2 PATHOGENESIS AND COMMENSALISM OF ENTEROBACTERIA
      • TEAM 3 INTESTINAL NEURO-IMMUNE INTERACTIONS
      • TEAM 4 GENETICS AND REGULATION OF IRON METABOLISM
      • TEAM 5 ERYTHROFERRONE AND IRON HOMEOSTASIS
      • RESEARCH GROUP ENVIRONMENT & INTESTINAL EPITHELIUM INTERACTIONS -EINSTEIN-
    • Core facilities >
      • DIGESTIVE MODELS
      • ORGANOIDS
    • Publications >
      • Help for scientific writing
  • EDUCATION
    • MASTER
    • THESIS >
      • THESIS TOPICS PROPOSALS
      • THESIS DEFENSES
  • JOBS
    • JOB OFFERS >
      • GROUP LEADER
    • PREPARATION FOR COMPETITION
  • Events
    • IRSD Retreat >
      • 2016
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    • Progress Reports
    • IRSD seminars
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​

RESEARCH ENGINNEER

céline besson 

CONTACTS

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00 33 (0)5 62 74 45 07
TEAM 4 :  GENETIC AND REGULATION OF IRON METABOLISM 
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Mini CV

EDUCATION
  • Master professionnel Génétique, Physiologie, Biotechnologie, Limoges 2005
  • IUP Ingénieurie de la Santé, Montpellier, 2004
  • DUT ABB, Clermont-Ferrand, 2002​
RESEARCH RELATED EXPERIENCE
  • ​Ingénieur d’études, équipe H. Coppin / MP. ROTH​ Depuis 2008.
  • Ingénieur d’études, équipe P. Hovnanian, Inserm U563, Toulouse Purpan (2005-2008).

expertise

Quantitative PCR, western blot, histology , immunofluorescence, confocal microscopy



 RESEARCH/PROJECT

Iron metabolism regulation during inflammatory and infectious processes

SCIENTIFIC PRODUCTION 

Further support for the association of GNPAT variant rs11558492 with severe iron overload in hemochromatosis. Besson-Fournier C, Martinez M, Vinel JP, Aguilar-Martinez P, Coppin H, Roth MP.Hepatology. 2016 Jun;63(6):2054-5. doi: 10.1002/hep.28259. Epub 2015 Oct 30. No abstract available.

Differing impact of the deletion of hemochromatosis-associated molecules HFE and transferrin receptor-2 on the iron phenotype of mice lacking bone morphogenetic protein 6 or hemojuvelin.Latour C, Besson-Fournier C, Meynard D, Silvestri L, Gourbeyre O, Aguilar-Martinez P, Schmidt PJ, Fleming MD, Roth MP, Coppin H.
Hepatology. 2016 Jan;63(1):126-37.
 
Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin.
Latour C, Kautz L, Besson-Fournier C, Island ML, Canonne-Hergaux F, Loréal O, Ganz T, Coppin H, Roth MP.
Hepatology. 2014 Feb;59(2):683-94.
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Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling.
Besson-Fournier C, Latour C, Kautz L, Bertrand J, Ganz T, Roth MP, Coppin H.
Blood. 2012 Jul 12;120(2):431-9
 
Iron overload induces BMP6 expression in the liver but not in the duodenum.
Kautz L, Besson-Fournier C, Meynard D, Latour C, Roth MP, Coppin H.
Haematologica. 2011 Feb;96(2):199-203.
 
BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.
Kautz L, Meynard D, Besson-Fournier C, Darnaud V, Al Saati T, Coppin H, Roth MP.
Blood. 2009 Sep 17;114(12):2515-20
 

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INSERM IRSD U1220 , CHU PURPAN PLACE DU DOCTEUR BAYLAC, 
​CS 60039 31024, TOULOUSE CEDEX 3  
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 00 33 (0)5 62 74 45 03   
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