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  • HOME
  • About
    • DIRECTION
  • Research
    • teams >
      • TEAM 1 PATHOPHYSIOLOGY OF THE INTESTINAL EPITHELIUM
      • ​TEAM 2 PATHOGENESIS AND COMMENSALISM OF ENTEROBACTERIA
      • TEAM 3 INTESTINAL NEURO-IMMUNE INTERACTIONS
      • TEAM 4 IRON METABOLISM: FROM REGULATION TO THERAPY
      • TEAM 5 ERYTHROFERRONE AND IRON HOMEOSTASIS
      • TEAM6 ENVIRONMENT & INTESTINAL EPITHELIUM INTERACTIONS -EINSTEIN-
    • Core facilities >
      • DIGESTIVE MODELS
      • ORGANOIDS
    • Publications >
      • Help for scientific writing
  • EDUCATION
    • MASTER
    • THESIS >
      • THESIS TOPICS PROPOSALS
      • THESIS DEFENSES
  • JOBS
    • JOB OFFERS >
      • GROUP LEADER
    • PREPARATION FOR COMPETITION
  • Events
    • IRSD Retreat >
      • 2016
      • 2017
    • Progress Reports
    • IRSD seminars
  • SERVICES
  • Highlights
  • Pictures
  • Contacts
    • Contact IRSD
    • Contact team
    • Contact Core Facilities
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DOCTORANT (pharm)
CHU-UPS

PhD student

christophe garcie

contact

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00 33 (0)5 31 54 79 48
EQUIPE 2 : PATHOGÉNIE ET COMMENSALISME DES ENTEROBACTÉRIES
TEAM 2 : PATHOGENESIS AND COMMENSALISM OF ENTEROBACTERIA
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Mini CV

  • 2014 : Diplôme de Docteur en Pharmacie – Diplôme d’études spécialisées de Biologie Médicale (Bactériologie)/PharmD – Specialist in Laboratory Medicine (Bacteriology)

  • 2012 : Diplôme de Master 2 Recherche/MSc

Recherche/projet  research/project

​Molecular bases of commensalism and pathogenesis of enterobacteria
Biosynthèse de la colibactine, une génotoxine de Escherichia coli

Production scientifique scientific production 

​• Garcie C., Tronnet S., Garénaux A., McCarthy A.J., Brachmann A.O., Pénary M, Houle S., Nougayrède J.P., Piel J., Taylor P.W., Dozois C.M., Genevaux P., Oswald E. and Martin P. The stress-responsive Hsp90 chaperone is required for the production of genotoxin and siderophore by pathogenic Escherichia coli. J Infect Dis. 2016;214(6):916-24.
• Tronnet S., Garcie C., Rehms N., Dobrindt U., Oswald E., Martin P. Iron homeostasis regulates the genotoxicity of Escherichia coli producing colibactin. Infect Immun. 2016 pii: IAI.00659-16. [Epub ahead of print].
• Brachmann A.O., Garcie C., Wu V., Martin P., Ueoka R., Oswald E. and Piel J. Colibactin biosynthesis and biological activity depend on the rare aminomalonyl polyketide. Chemical Communications. 2015). DOI:10.1039/c5cc02718g
• Martin P., Marcq I., Magistro G., Penary M., Garcie C., Payros D., Boury M., Olier M., Nougayrède J.P., Audebert M., Chalut C., Schubert S. and Oswald E. Interplay between Siderophores and Colibactin genotoxin biosynthetic pathways in Escherichia coli. PLOS Pathogens (2013). 9:e1003437

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