Mini CV
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personal interestBacterial biofilms in the context of intestinal infectious and inflammatory diseases
key wordsBiofilms and Intestinal Microbiota, Inflammatory Bowel Diseases, Inflammation, Intestinal Epithelial Cells, Proteases/Antiproteases , Enteropathogenic Infections
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Recherche/projet research/project
Enterobacterial infections and dysbyosis in metabolic diseases, gut inflammation and cancer
Production scientifique scientific production
selected articles
- Motta JP., Allain T, L. G-H, Groves R, T. F, H. R, Beck P, Lewis I, Wallace JL, and Buret A. "Iron Sequestration in Microbiota Biofilms As A Novel Strategy for Treating Inflammatory Bowel Disease" (2018) Inflammatory Bowel Diseases accepted 02/2018
- Motta, JP., K. L. Flannigan, T. A. Agbor, J. K. Beatty, R. W. Blackler, M. L. Workentine, G. J. Da Silva, R. Wang, A. G. Buret and J. L. Wallace (2015). "Hydrogen Sulfide Protects from Colitis and Restores Intestinal Microbiota Biofilm and Mucus Production." Inflammatory Bowel Diseases 21(5): 1006-1017.
- Bermudez-Humaran, L. G.*, JP. Motta*, C. Aubry, P. Kharrat, L. Rous-Martin, J. M. Sallenave, C. Deraison,
- N. Vergnolle* and P. Langella* (2015). "Serine protease inhibitors protect better than IL-10 and TGF-beta anti-inflammatory cytokines against mouse colitis when delivered by recombinant lactococci." Microbial Cell Factories 14(26). doi:10.1186/s12934-015-0198-4
- Motta, JP.*, L. G. Bermudez-Humaran*, C. Deraison, L. Martin, C. Rolland, P. Rousset, J. Boue, G. Dietrich, K. Chapman, P. Kharrat, J. P. Vinel, L. Alric, E. Mas, J. M. Sallenave, P. Langella* and N. Vergnolle* (2012). "Food-Grade Bacteria Expressing Elafin Protect Against Inflammation and Restore Colon Homeostasis." Science Translational Medicine 4(158).
- Motta, JP.*, L. Magne*, D. Descamps, C. Rolland, C. Squarzoni-Dale, P. Rousset, L. Martin, N. Cenac, V. Balloy, M. Huerre, L. F. Frohlich, D. Jenne, J. Wartelle, A. Belaaouaj, E. Mas, J. P. Vinel, L. Alric, M. Chignard, N. Vergnolle* and J. M. Sallenave* (2011). "Modifying the Protease, Antiprotease Pattern by Elafin Overexpression Protects Mice From Colitis." Gastroenterology 140(4): 1272-1282.
- Motta, JP., L. Martin and N. Vergnolle (2011). Proteases/Antiproteases in Inflammatory Bowel Diseases. Proteases and Their Receptors in Inflammation., Springer Basel: 173-215.